What is Panadol?
In fact, what really works is a drug called paracetamol (Acetaminophen), which has a special effect on fever and pain relief, so it is widely used in many antipyretic drugs.
Related trade name: Panadol (must understand), Tylenol (Tylenol), Paracetamol (paracetamol) and so on.
Drug pregnancy grade: AU: A, US: B
- Category A: there was no risk to the fetus (and no evidence of risk in the middle and third trimester) in early pregnant women with a control group, and there might be minimal harm to the fetus;
- Classification B: there is no risk to the fetus in animal reproduction tests, but no maternal control, or side effects to animal reproduction tests (less sterile). However, in the control group of early pregnant women, the side effects were not confirmed (and there was no dangerous evidence in the middle and third trimester).
Administration: oral, rectal or intravenous
Why can Panadol stop the pain?
In fact, modern medicine does not fully understand how it works! Yes, you're right!
The prevailing view now is that acetaminophen acts in a way similar to aspirin and ibuprofen by inhibiting cyclooxygenase. Others believe that the ultimate effect is to block the pain-sensing nerve of the brain to achieve pain relief. But no one dares to say that he really grasped the principle, and all the conclusions are now based on a large number of test results.
Can Panadol get rid of inflammation?
Very weak, according to pharmacist friends, although acetaminophen can be used to treat inflammatory pain, but it is not a non-steroidal anti-inflammatory drug (NSAID), because its anti-inflammatory effect is very weak. So for inflammation, taking Panadol can only relieve symptoms, does not solve the fundamental problem.
Does Panadol have any side effects? What side effects do you have?
It's a triple poison, which is a caveat from our ancestors. Similarly, Panadol has side effects, and its side effect is that it produces a small amount of toxic metabolite NAPQI (N-acetyl-p-benzoquinone imine), which requires the liver to break down during the metabolic process. If taken in strict accordance with instructions and doctor's instructions, it should be safe, but do not overdose.
If taking too much and exceeding the load of liver catabolism, the level of NAPQI in the body will be higher, and the liver function will be damaged. Some side effects, such as nausea, stomachache, jaundice, and even acute liver failure, will occur. This kind of damage is irreversible.
It's not alarmist, 8000 Australians are poisoned by Panadol every year and more than 150 patients are sent to hospital every week because of Panadol poisoning, experts say the problem is getting worse. Panadolescence is used in 1/5 of the cases of intentional poisoning in emergency rooms across Australia, the new study found. Can you believe that? If you eat too much, it's poison!
Is Panadol a universal painkiller?
Of course not, Panadol has a limited effect on chronic pain, and according to previous studies of arthralgia patients taking Panadol for pain relief, seven studies have compared the effects of Panadol to placebo. Of the seven studies, five concluded that the effect of Panadol was only slightly better, while the other two concluded that the effect was no different.
Classification of Panadol
Here we can only give a rough introduction to the type of Panadol, because there are 27 open-shelf products in supermarkets and pharmacies, not to mention family clothes, Walkman bags, and so on. In general, there are four categories: children's medication, common painkillers, muscle and joint painkillers, and cold-cold series, and be sure to buy the right type according to your needs and doctor's advice.
Dispute over Panadol
The biggest controversy is the risk of drugs, and the main side effect of overdose Panadol is liver damage. Not only that, more serious side effects were recently discovered by British doctors, and in 2011 Michael Doherty (Michael Doherty) of the Nottingham City Hospital published a study.
He followed 892 patients who had been taking Panadol for a long time, and when Dolty saw the results of blood tests on patients taking Panadol, he was shocked: hemoglobin, the protein that carries oxygen in the blood, is dropping rapidly. And red blood cells are getting smaller and lighter. The most logical explanation for this is that the patient has internal bleeding and a considerable amount of bleeding.
In March 2014, the International Association for Osteoarthritis Research changed its guidelines on Panadol to "uncertainty", reflecting growing concerns about the drug's safety. Such concerns seem to have raised similar concerns in the UK.
In August 2013, NICE's new version of the guidelines for Osteoarthritis removed the recommendation to use Panadol as its preferred drug of choice, and identified it as a potential hazard. "through a comprehensive balance, the benefits of Panadol in controlling symptoms are no longer offset by its risk," the report wrote. But when the official version was released, it was removed again, causing discontent among responsible doctors.
In addition, because Panadol is an over-the-counter drug, it is very easy to buy, and it is often abused. Some young people who do not know how to use it even use it as a drug, thus causing some social problems. Perhaps there is a need for more caution and stricter control.
Take the correct posture for Panadol
So what should we all do to Panadol?
First of all, realize that God's medicine is not God, eating wrong, eating too much will have problems, the attitude to drugs must be cautious.
Second, understand whether your pain really needs to be taken to get rid of the drug, consult a pharmacist or doctor more, and different pain may have better alternatives. For example, for chronic pain, perhaps Panadol is not appropriate.
Finally, dose! The important thing to say three times, please follow the dose instructions strictly, once found no effect after taking, immediately stop and consult their own GP. In addition, do not drink while taking Panadol to avoid increasing the liver burden and causing damage.
In short, medicine is medicine, not candy, everyone should be careful, hope this article will help you, let you know more about Panadol oh.
