Recently, the medical profession in the attack and defense war with cancer has produced new results! Its emergence may have an inter-epoch significance of lifting cancer patients immersed in pain out of chemotherapy, allowing cancer to "turn back" before it is in the limelight of the human body, and it makes cancer less terrifying. No more intimidating, no longer "cancer" as a person and even a family's biggest killer.
According to the media < Daily Mail > on March 28, a new cancer "vaccine" has been successfully developed!
When scientists experimented with cancer in experimental mice, 97% of mice with arterial tumors were successfully cured by the vaccine.
Even more exciting is that the successful development of the vaccine does not appear to be the end of the end, because the results of this study, will enter the market within a year!
Dailymail: a cancer vaccine successfully cured 97% of mice with aneurysms! No painful side effects! No chemo! Will be available in a year!
In the case of the vaccine, scientists say it will rid the body of the side effects of cancer drugs and cure some cancers without pain or self-destructions, and, of course, with the vaccine, there is little to be done with chemotherapy.
In terms of detail, Dailymail also reported the following points:
The only slight discomfort is that the vaccine contains two safe drugs that may cause fever and pain in the injection site, but the vaccine has no side effects.
Scientists believe that once approved, the vaccine will be available in full over a year to two years.
So how does the vaccine work to cure cancer? Can it really reach the greatest opponent of life as people expect it to be?
Compared to previous cancer drugs, this new cancer vaccine is really different!
Traditional cancer drugs or vaccines often protect against cancer by creating as much as possible a lasting immunity against cancer. But this vaccine is different, it does not deliberately create immunity in the human body, this method is a little single, so how does it do it?
Scientists think that the word "creation" seems too small in front of the natural human body, the human body such a complex and huge system, probably will look down on the human self-created things.
Therefore, instead of creating an immune system, it is better to make use of the immune system of the human body itself directly!
This is the most powerful weapon given to the human body by nature!
That's exactly how the vaccine works. It activates the body's own immune system through drug stimulation, and then attacks aggressive diseases such as aneurysms and lymphoma through the body's own immune system. Even leukemia.
Dr. Ronald Levy, professor and lead researcher of oncology at Stanford University, and Etit Sajiv-Buffy, professor of oncology at Stanford, presented the results of the mouse trial to the world: in the case of lymphoma, In a study of 90 mice with cancers such as breast and colon cancer, the new therapy eliminated cancer tumors in 87 mice, with a cure rate of 97%, even if the tumor had spread to other parts of the body.
"We've seen amazing, systemic effects," said Ronald Levy, a professor of oncology and senior author of the study, "and all the tumors in these animals have been removed!" said Ronald Levy, a professor of oncology and a senior author of the study.
The trial was published in the January issue of the journal Science Transforming Medicine and scientists say that once the vaccine is available, lymphoma and leukemia will no longer be scary!
So is this treatment for cancer still effective in the human body?
To understand this, we must first clarify two concepts:
1, how does malignant tumor spread?
2. What is human immune T cell (T Cell)?
In short, malignant tumors are made up of cancer cells, whose growth is usually uncontrolled, and which not only grow rapidly, but also find ways to spread to other tissues.
Usually, cancer cells enter all parts of the body through the body's blood and lymph. As the cells continue to divide, the tumor gets bigger and bigger, stimulating the development of blood vessels to "replenish" oxygen and nutrients (such as protein). This growth may enter new areas by putting pressure on the surrounding area, using an enzyme to decompose cells or tissues.
Immune T cell (T Cell) is a kind of lymphocyte and plays an important role in immune response. There are many different types of T cell, among which the most virulent is cytotoxic T cell (killer T cell). These cells function like a "killer" or a cytotoxin, because they kill target cells that produce specific antigen responses and destroy infected or mutated cells.
However, with the development of tumors, anti-tumor measures will be taken to inhibit the activity of T cells, which means that the human body will no longer have the ability to resist.
Remember from the above, this new cancer vaccine relies on activation of the human immune system to eliminate cancer cells, yes, the drug is activated by cytotoxic T cells!
The new therapy works by reactivating suppressed T cells, by injecting the "vaccine" directly into the tumor, activating the surrounding T cells that were once suppressed, and continuing to fight, "one I fell down," But there are tens of thousands of me standing up!
The therapy, known as immunotherapy, stimulates immune T cells and induces them to attack cancer cells.
In animal experiments, injecting drugs into one tumor eliminates tumors in other parts of the body-because active T cells migrate to other parts of the body and destroy spread tumors. And in many cases, this treatment can also prevent future tumours. At the same time, the drug also rapidly binds to rapidly reproducing cell membranes, targeting specific enzymes that prevent the spread of tumors, greatly slowing the spread of cancer cells, and also preventing cancer cells from attaching to the proteins they need. Fundamentally "hijacked" the survival mechanism of cancer cells!
In general, the new vaccine can kill spreading cancer cells by activating the immune system, on the other hand, it can also give cancer cells "out of food" to stop the spread of cancer cells! Two methods of two-pronged, so that cancer cells nowhere to escape!
So strictly speaking, the new therapy is not a vaccine, but involves a step similar to vaccination. The therapy can be called immunotherapy.
So what is the probability of approval for such a new drug based on immunotherapy? Is it possible, like a lot of drugs, that it started to be strong, and finally disappeared? The answer given by scientists is that the drug is highly likely to be approved!
Immunotherapy is not new, and several immunotherapies have been approved for cancer.
For example, CAR-T cell therapy, recently approved for the treatment of certain leukemia and lymphoma, allows specific immune cells in patients to be genetically modified to fight cancer by extracting specific immune cells from patients.
But one of the advantages of the new treatment over CAR-T cell therapy, the researchers say, is that it does not require genetic modification of patients' immune cells. In other words, the new drug reduces side effects on the basis of immunotherapy, which is safer, more effective, and possibly cheaper than the previous CAR-T immunotherapy.
It is well known that patients receiving CAR-T therapy may need to spend nearly $500000 on treatment and may cause fever, disorder, organ failure and immune system dysfunction, and this new drug, which has been tested, There would be no such danger.
The drug, which will be tested for the first time at the end of this year, has been convened by Stanford University School of Medicine to pass about 35 participants to see if the drug works for "bowel cancer" and "breast cancer."
Scientists predict that, if approved, humans around the world will see the drug on the market within a year or two.
Both drugs have been approved for use in humans by the time they are published, and are safe. The experiment is testing their combination. After that, once the FDA really approves the birth, the dawn of cancer patients is in sight!
This new drug discovery is an important progress in immunotherapy and in the final conquest of cancer patients. Cancer, as the first killer of human beings in the past hundred years, has been constantly conquered by human science in recent years. From the Black death in the Middle Ages to cholera at the end of the 20th century, many of the diseases that had done whatever they wanted were subdued at the foot of science.
Soon, the new drug will be tested in humans in a phase one trial to test its practical efficacy in vivo. Two of the drugs will also be approved for trial approval, and in the near future, after crossing the black death and cholera mountains, Humans may really conquer cancer, the centuries-old range..
Finally, we would like to pay the highest tribute to the scientists who stand on the front line of cancer, who use hard work and knowledge to bring the gospel of survival to groups of patients.
Scientists must cheer up, the eyes are looking forward to the future of life is looking forward to this day, a new anti-cancer vaccine, we will not be separated in a year.