In the early 1990s, something very strange happened in Europe: a group of healthy women developed glomerulonephritis and rapidly developed kidney failure.
A lot of research revealed what these women had in common: they all took a special cold drug. Since then, Western countries have joined forces with the boycott to ban such cold drugs.
However, nearly 30 years later, this kind of cold medicine, but still lie quietly in the drawers of the vast majority of Chinese!
Recently, a powerful essay from the authoritative medical journal Science Translation Medicine, widely circulated in the medical profession, once again issued a warning to all Chinese: please throw away all of the medicine in your family immediately!
Recently, Scientific Transforming Medicine published an important study and suggested that toxic herbs containing "aristolochic acid" are one of the major causes of liver cancer in Asia (especially in the TW region of China and in the mainland).
China is a kidney disease, kidney cancer country, is also a liver cancer country. In 2015, China added more than four hundred thousand new liver cancer patients, accounting for more than half of the world. The average risk of liver cancer in China is 4 times higher than that of Europe and America.
In the past, we attributed it to the widespread spread of viral hepatitis and improper grain storage (aflatoxin). But this new study, essay, has led us to discover a direct cause that could be even more damaging.
The cause is that the majority of Chinese people often eat cold medicine, cough medicine and dehumidifying and analgesic medicine wine, all contain aristolochia ingredient, that is the true name of the carcinogen.
Everyone should know about the harm of aristolochic acid.
01 what is "aristolochic acid"
Let's talk about aristolochic acid first.
Aristolochic acid (AA) is a secondary metabolite in almost all plants of the genus Aristolochia. Because it causes renal tubule dysfunction, it also has a nickname, "nephrotoxin," which can eventually lead to renal failure.
The European women at the beginning of the article, they take cold Chinese medicine, there is a common medicine-Guang self-defense.
Broad self-defense, traditionally used for analgesia, diuresis, lowering blood pressure and so on. After a lot of scientific research, the key problem is that Guangfangji is rich in aristolochic acid. Since then, there has been a brand-new medical term in the world: Chinese Herbal Nephropathy (Chinese herbs nephropathy,) short for CHN).
The danger was known a long time ago. There are more than 600 species of aristolochic acid in the world, 65 of which are traditional Chinese medicine.
02 "aristolochic acid" is one of the strongest known carcinogens
As early as 1994, France's government launched a global wave of anti-aristolochic acid by banning the sale of all Chinese medicines suspected of containing aristolochic acid because of its severe nephrotic response.
In subsequent investigations, medical scientists found that aristolochic acid causes kidney disease, only a small part of its damage, and that aristolochic acid causes most of it, urinary tract cancer.
Experiments have shown that aristolochic acid causes the disease because it binds closely to DNA, leading to the easy conversion of T into A and A into T (DNA with T, C, G, A encoding life at the time of cell replication. Also known as the "aristolochic acid mutation".
In other words:
Just like you wrote a letter to the goddess, it was "Wo Ai Ni" (I love you). As a result, when aristolochic acid was combined, A became T and became "Wo Ti Ni" (I kicked you). If you send this letter, you won't have sex with the Goddess.
How strong is the carcinogenic ability of aristolochic acid? TW scientists have found an average of 150 mutations per 1 million DNA, in cancer of the urinary tract caused by aristolochic acid.
What is this concept?
Is lung cancer scary enough? Lung cancer caused by smoking has an average of 8 mutations per 1 million DNA. And this 8 compared to the 150 of aristolochic acid, is simply a small witch to see the super-wizard.
In fact, aristolochic acid is one of the strongest known carcinogens. Remember, this is 100% natural poison, so don't superstition "pure natural, harmless" such nonsense.
03 Global boycott, Chinese often eat!
Ten years after the first wave of anti-aristolochic acid in the world, China's government imposed a ban on individual medicines containing aristolochic acid.
But as early as 1964, Wu Hansong, a Chinese scholar, reported two cases of extreme kidney failure caused by Guan Mu Tong decoction.
That year there was an article called "one poison, two treatment."
Due to national conditions, until 2017 (30 years have passed since aristolochic acid was proved toxic.) Chinese herbs containing aristolochic acid are still marketed in Chinese and overseas pharmacies.
One Rentang has claimed that aristolochic acid is harmless, domestic medical journals have also published many do not know how to do it, claiming that the Chinese aristolochic acid Chinese medicine is not toxic to animals essay.
When the world is resisting aristolochic acid, Chinese dolls and old people are still sending it to their bellies! Lamentable, pathetic, pitiful ~
03 these drugs are all "aristolochic acid".
Here is a list of Chinese herbs known or suspected to contain aristolochic acid:
Aristolochia aristolochia, Aristolochia sinensis, Tianxianteng, Amur, Guangfengji, Hanzhong Fangji, Asarum, Fangfeng, Bones, Huai Tong, Jusha Lotus, Triple Tube, du Heng, Guannan incense, Southern cassava, Fuxiang, Snake back, false Big Potato, Butterfly darkening, Blood Thunder, Platinum Fruit Lam, Gold earrings, Black Grass, Alpine, Purple, Aconitum, Kawamitong, Preknowledge son, Wood self-defense, Clematis, Wulingxian, incense self-defense, White English, White hair Rattan, Big Green Wood incense, and so on.
See this, maybe someone will say, "these Chinese medicine I have not heard of, usually do not eat at all!" What if they all contain aristolochic acid? "
TOO YOUNG! TOO NAIVE！
It is true that these herbs are far from ordinary people's lives, but they are used as medicinal materials to make cold medicine, cough medicine and dehumidifying and analgesic medicine, which are very close to our lives.
Here is a list of proprietary Chinese medicines containing aristolochic acid, most of which can be found in many family drawers. Now, you can find them all and throw them in the trash:
Chuanxiling capsule, Fei'an tablet, compound Shedanchuan Bei San, Jiming Pill, Jisu Pill, Seventy Weisong Stone Pill, Thirteen Weiwei Shugan capsule, Weifu granule, Xiaoke Pingchuan Oral liquid, Xinbitao tablet, Xiangteng capsule, Eucommia Zhuang Bone Pill, Fengshining medicinal wine, compound rheumatic medicine wine, compound boxing ginseng tablet, dispelling wind and dehumidifying medicine wine, Shaolin Zhenggu essence, injured dampness and relieving pain cream, Shenshen pesticide wine, Jinzhu Zhixie tablet, Baowei capsule, compound Weitong capsule, Kowloon detoxification capsule, three snake medicine wine, Longdan Xiegan Pill, Deafness Pill, Bazheng Pill, Pure Yang Zhengqi Pill, Dahuang Qingwei Pill, Danggui Sini decoction, Daoji Pill, mannan Disinfection Pill, Paishi granule, Diedawan, Gynecology Fenqing Pill, Guanxinsuhe Pill, Xincatan Pill, Shi Xiang Hui Sheng Pill, Ji Sheng Orange Core Pill, Zhike Huatan Pill, Bazheng mixture, Pediatric Jindan tablet, Fuqingwu Pill, Anyang refined Ointment, Child Qingfei Pill, Jiuwei Qiang Huo Wan, Chuanjie Tea regulating Pill, Children Kechuan granule, Xiaoqinglong mixture, Monzao Powder.
04 put aside the measurement of toxicity, are all hooligans?
Aristolochic acid is a hooligan! After this heavy-pound essay came out, people were lucky enough to think that there should be no problem eating less?
After all, it is not often said that leaving the dose to talk about toxicity is to play hooligans!
Wrong! As early as 2013, scientists discovered the carcinogenic mechanism of aristolochic acid, its metabolite dA-AAI, which forms an adduct with human DNA and requires only one small base to be entangled to mutate and cancer can occur.
There is no so-called safety threshold for this class 1 carcinogen, mutagens-induced DNA damage. The more you eat, the more likely you are to have a liver cancer outbreak.
Therefore, there is no safe dose of aristolochic acid. Even one milligram can cause cancer.
And, "after 20 years of ingestion of aristolochic acid herbs, biopsies can still find a metabolite of aristolochic acid." Can be described as a mistakenly drink, causing endless harm.
If the box meal for the child is delicious and good-looking, the child will not only be happy, in front of the small partner will also have more face. Finally, some people will ask, then I have a cold cough always need to take medicine? Do not eat some cough Huatan capsule, sick ah!
The first reaction to this is not to get rid of the cancer-causing drugs on it,
I can only say: then eat it! After all, liver cancer is the next thing, the urgent task is to quickly cure the cold cough, after recovery to control the liver cancer.
After all, there is an idiom called "drink poison to quench thirst"!
05 "bullshit, what can be wrong with old ancestors?"
"then our ancestors have used these herbs for thousands of years, why nothing?" this is a very good question. Scientists say aristolochic acid is a potent carcinogen that causes kidney failure.
At the same time, the old ancestors with aristolochic acid-containing Chinese medicine, most people will not have a major problem. At first glance, it seems unexplainable, but the reason is simple:
My ancestors died early!
Whether chronic renal failure or cancer of the urinary tract, it takes a long time to accumulate. Even if drinking carcinogenic Chinese medicine every day, if the amount is not large, persistent poison for about 10 years, 20 years, serious problems will appear.
Don't worry about aristolochic acid if you're going to hang up around 40, like your ancestors. But if you want to live healthy to 80, believe in objective evidence and modern science.
Conclusion of 06
Traditional culture, including traditional medicine, has something to inherit. But in the 21st century, everything has to be retested by the objective test of science, taking its essence and removing its dross.
The scientific attitude and method, is the premise that lets the Chinese medicine truly go to the world. Artemisinin and arsenic are examples.
Drugs should not be divided into traditional Chinese medicine and western medicine, should be divided into good than harm drugs, and harm more than good drugs.
Finally, the task of this article is to remind you to be more careful, because whether in Australia or in the domestic, a large number of aristolochic acid containing medicinal materials and traditional Chinese medicine, is still in use, still in sales!
Plus folk prescription, formula is popular, so-called "partial prescription to cure serious disease", aristolochic acid is still very likely to poison people around you.
Please remind them!